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- Document type:
- Comment; Journal Article; Editorial Material
- Author(s):
- Protzer, Ulrike
- Title:
- Hepatitis: Epigenetic control of HBV by HBx protein--releasing the break?
- Abstract:
- HBV persists by depositing covalently closed circular DNA (cccDNA) into the nucleus of infected host cells. HBV X protein (HBx) is a crucial determinant for regulating HBV activity, but the molecular details have not been fully understood. A new role for HBx in regulating cccDNA transcription has now been identified.
- Journal title abbreviation:
- Nat Rev Gastroenterol Hepatol
- Year:
- 2015
- Journal volume:
- 12
- Journal issue:
- 10
- Pages contribution:
- 558-9
- Language:
- eng
- Fulltext / DOI:
- doi:10.1038/nrgastro.2015.152
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/26323877
- Print-ISSN:
- 1759-5045
- TUM Institution:
- Institut für Virologie
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