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Dokumenttyp:
journal article 
Autor(en):
Kamp, Florian; Cabal, Gonzalo; Mairani, Andrea; Parodi, Katia; Wilkens, Jan J; Carlson, David J 
Titel:
Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra. 
Abstract:
The physical and biological differences between heavy ions and photons have not been fully exploited and could improve treatment outcomes. In carbon ion therapy, treatment planning must account for physical properties, such as the absorbed dose and nuclear fragmentation, and for differences in the relative biological effectiveness (RBE) of ions compared with photons. We combined the mechanistic repair-misrepair-fixation (RMF) model with Monte Carlo-generated fragmentation spectra for biological...    »
 
Zeitschriftentitel:
Int J Radiat Oncol Biol Phys 
Jahr:
2015 
Band / Volume:
93 
Heft / Issue:
Seitenangaben Beitrag:
557-68 
Sprache:
eng 
Print-ISSN:
0360-3016 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie