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Document type:
journal article 
Author(s):
Schmitt, Andreas; Rödel, Philipp; Anamur, Cihad; Seeliger, Claudine; Imhoff, Andreas B; Herbst, Elmar; Vogt, Stephan; van Griensven, Martijn; Winter, Gerhard; Engert, Julia 
Title:
Calcium alginate gels as stem cell matrix-making paracrine stem cell activity available for enhanced healing after surgery. 
Abstract:
Regeneration after surgery can be improved by the administration of anabolic growth factors. However, to locally maintain these factors at the site of regeneration is problematic. The aim of this study was to develop a matrix system containing human mesenchymal stem cells (MSCs) which can be applied to the surgical site and allows the secretion of endogenous healing factors from the cells. Calcium alginate gels were prepared by a combination of internal and external gelation. The gelling behavio...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2015 
Journal volume:
10 
Journal issue:
Pages contribution:
e0118937 
Language:
eng 
TUM Institution:
Abteilung für Sportorthopädie; Klinik für Unfallchirurgie