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Dokumenttyp:
journal article 
Autor(en):
Heck, Angela; Fastenrath, Matthias; Coynel, David; Auschra, Bianca; Bickel, Horst; Freytag, Virginie; Gschwind, Leo; Hartmann, Francina; Jessen, Frank; Kaduszkiewicz, Hanna; Maier, Wolfgang; Milnik, Annette; Pentzek, Michael; Riedel-Heller, Steffi G; Spalek, Klara; Vogler, Christian; Wagner, Michael; Weyerer, Siegfried; Wolfsgruber, Steffen; de Quervain, Dominique J-F; Papassotiropoulos, Andreas 
Titel:
Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease. 
Abstract:
Human episodic memory performance is linked to the function of specific brain regions, including the hippocampus; declines as a result of increasing age; and is markedly disturbed in Alzheimer disease (AD), an age-associated neurodegenerative disorder that primarily affects the hippocampus. Exploring the molecular underpinnings of human episodic memory is key to the understanding of hippocampus-dependent cognitive physiology and pathophysiology.To determine whether biologically defined groups...    »
 
Zeitschriftentitel:
JAMA Psychiatry 
Jahr:
2015 
Band / Volume:
72 
Heft / Issue:
10 
Seitenangaben Beitrag:
1029-36 
Sprache:
eng 
Print-ISSN:
2168-622X 
TUM Einrichtung:
Klinik und Poliklinik für Psychiatrie und Psychotherapie