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Dokumenttyp:
journal article 
Autor(en):
Ly, Alice; Buck, Achim; Balluff, Benjamin; Sun, Na; Gorzolka, Karin; Feuchtinger, Annette; Janssen, Klaus-Peter; Kuppen, Peter J K; van de Velde, Cornelis J H; Weirich, Gregor; Erlmeier, Franziska; Langer, Rupert; Aubele, Michaela; Zitzelsberger, Horst; McDonnell, Liam; Aichler, Michaela; Walch, Axel 
Titel:
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue. 
Abstract:
Formalin-fixed and paraffin-embedded (FFPE) tissue specimens are the gold standard for histological examination, and they provide valuable molecular information in tissue-based research. Metabolite assessment from archived tissue samples has not been extensively conducted because of a lack of appropriate protocols and concerns about changes in metabolite content or chemical state due to tissue processing. We present a protocol for the in situ analysis of metabolite content from FFPE samples usin...    »
 
Zeitschriftentitel:
Nat Protoc 
Jahr:
2016 
Band / Volume:
11 
Heft / Issue:
Seitenangaben Beitrag:
1428-43 
Sprache:
eng 
Print-ISSN:
1754-2189 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; Institut für Allgemeine Pathologie und pathologische Anatomie