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Document type:
journal article 
Author(s):
Fierro, Fernando A; O'Neal, Adam J; Beegle, Julie R; Chávez, Myra N; Peavy, Thomas R; Isseroff, Roslyn R; Egaña, José T 
Title:
Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. 
Abstract:
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity. These characteristics, however, are mostly studied under standard in vitro culture conditions. In contrast, various novel cell-based therapies imply pre-seeding MSC into bio-artificial scaffolds. Here we describe human bone marrow-derived MSC seeded in Integra matrices, a common type of scaffold for dermal regeneration (SDR). We show and m...    »
 
Journal title abbreviation:
Front Cell Dev Biol 
Year:
2015 
Journal volume:
Pages contribution:
68 
Language:
eng 
Print-ISSN:
2296-634X 
TUM Institution:
Klinik und Poliklinik für Plastische Chirurgie und Handchirurgie