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Document type:
journal article 
Author(s):
Jacob, Simon N; Stalter, Maximilian; Nieder, Andreas 
Title:
Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex. 
Abstract:
The prefrontal cortex (PFC) is crucial for maintaining relevant information in working memory and resisting interference. PFC neurons are strongly regulated by dopamine, but it is unknown whether dopamine receptors are involved in protecting target memories from distracting stimuli. We investigated the prefrontal circuit dynamics and dopaminergic modulation of targets and distractors in monkeys trained to ignore interfering stimuli in a delayed-match-to-numerosity task. We found that dopamine D1...    »
 
Journal title abbreviation:
Nat Commun 
Year:
2016 
Journal volume:
Pages contribution:
13218 
Language:
eng 
TUM Institution:
Institut für Neurowissenschaften