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Dokumenttyp:
journal article 
Autor(en):
Koch, Kathrin; Myers, Nicholas E; Göttler, Jens; Pasquini, Lorenzo; Grimmer, Timo; Förster, Stefan; Manoliu, Andrei; Neitzel, Julia; Kurz, Alexander; Förstl, Hans; Riedl, Valentin; Wohlschläger, Afra M; Drzezga, Alexander; Sorg, Christian 
Titel:
Disrupted Intrinsic Networks Link Amyloid-? Pathology and Impaired Cognition in Prodromal Alzheimer's Disease. 
Abstract:
Amyloid-? pathology (A?) and impaired cognition characterize Alzheimer's disease (AD); however, neural mechanisms that link A?-pathology with impaired cognition are incompletely understood. Large-scale intrinsic connectivity networks (ICNs) are potential candidates for this link: A?-pathology affects specific networks in early AD, these networks show disrupted connectivity, and they process specific cognitive functions impaired in AD, like memory or attention. We hypothesized that, in AD, regio...    »
 
Zeitschriftentitel:
Cereb Cortex 
Jahr:
2015 
Band / Volume:
25 
Heft / Issue:
12 
Seitenangaben Beitrag:
4678-88 
Sprache:
eng 
Print-ISSN:
1047-3211 
TUM Einrichtung:
Abteilung für Neuroradiologie; Klinik und Poliklinik für Psychiatrie und Psychotherapie; Nuklearmedizinische Klinik und Poliklinik