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Document type:
journal article 
Author(s):
Höllerhage, Matthias; Rösler, Thomas W; Berjas, Magda; Luo, Rensheng; Tran, Kevin; Richards, Kristy M; Sabaa-Srur, Armando U; Maia, José Guilherme S; Moraes, Maria Rosa de; Godoy, Helena T; Höglinger, Günter U; Smith, Robert E 
Title:
Neurotoxicity of Dietary Supplements from Annonaceae Species. 
Abstract:
Dietary supplements containing plant materials of Annonaceae species (Annona muricata L., A. squamosa L., A. mucosa JACQ., A. squamosa × cherimola Mabb.) were extracted by hot, pressurized ethyl acetate and analyzed for their effect in vitro on Lund human mesencephalic neurons. Cell viability was measured by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, and cell death was determined by lactate dehydrogenase levels. Three supplements strongly decreased the cell viability...    »
 
Journal title abbreviation:
Int J Toxicol 
Year:
2015 
Journal volume:
34 
Journal issue:
Pages contribution:
543-50 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1091-5818 
TUM Institution:
Neurologische Klinik und Poliklinik