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Document type:
journal article 
Author(s):
Mücke, Thomas; Krestan, Christian R; Mitchell, David A; Kirschke, Jan S; Wutzl, Arno 
Title:
Bisphosphonate and Medication-Related Osteonecrosis of the Jaw: A Review. 
Abstract:
For patients with malignant disease taking bisphosphonates and denosumab, the incidence of medication-related osteonecrosis of the jaw (MRONJ) is up to 15% in contrast to 0.01% in patients with osteoporosis. Clinical presentation of MRONJ extends from asymptomatic exposure of bone in 94% of patients to severe cases of mandibular fractures in a minority of 4.5%. The strongest risk factors for MRONJ are invasive dental procedures and dental infections. Advances in imaging provide more preoperation...    »
 
Journal title abbreviation:
Semin Musculoskelet Radiol 
Year:
2016 
Journal volume:
20 
Journal issue:
Pages contribution:
305-314 
Language:
eng 
Print-ISSN:
1089-7860 
TUM Institution:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Abteilung für Neuroradiologie