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Dokumenttyp:
journal article 
Autor(en):
Maugg, Doris; Rothenaigner, Ina; Schorpp, Kenji; Potukuchi, Harish Kumar; Korsching, Eberhard; Baumhoer, Daniel; Hadian, Kamyar; Smida, Jan; Nathrath, Michaela 
Titel:
New small molecules targeting apoptosis and cell viability in osteosarcoma. 
Abstract:
Despite the option of multimodal therapy in the treatment strategies of osteosarcoma (OS), the most common primary malignant bone tumor, the standard therapy has not changed over the last decades and still involves multidrug chemotherapy and radical surgery. Although successfully applied in many patients a large number of patients eventually develop recurrent or metastatic disease in which current therapeutic regimens often lack efficacy. Thus, new therapeutic strategies are urgently needed. In...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2015 
Band / Volume:
10 
Heft / Issue:
Seitenangaben Beitrag:
e0129058 
Sprache:
eng 
TUM Einrichtung:
Kinderklinik und Poliklinik