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Dokumenttyp:
journal article 
Autor(en):
Jordens, MS; Keitel, V; Karababa, A; Zemtsova, I; Bronger, H; Haussinger, D; Gorg, B 
Titel:
Multidrug Resistance-Associated Protein 4 Expression in Ammonia-Treated Cultured Rat Astrocytes and Cerebral Cortex of Cirrhotic Patients with Hepatic Encephalopathy 
Abstract:
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome frequently accompanying liver cirrhosis and reflects the clinical manifestation of a low grade cerebral edema associated with cerebral oxidative/nitrosative stress. The multidrug resistance-associated protein (Mrp) 4 is an export pump which transports metabolites that were recently suggested to play a major role in the pathogenesis of HE such as neurosteroids and cyclic nucleotides. We therefore studied Mrp4 expression changes in ammonia...    »
 
Zeitschriftentitel:
Glia 
Jahr:
2015 
Band / Volume:
63 
Heft / Issue:
11 
Seitenangaben Beitrag:
2092-2105 
Sprache:
eng 
Print-ISSN:
0894-1491 
TUM Einrichtung:
Frauenklinik und Poliklinik