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Document type:
journal article 
Author(s):
Fazel, Julia; Rötzer, Silvia; Seidl, Christof; Feuerecker, Benedikt; Autenrieth, Michael; Weirich, Gregor; Bruchertseifer, Frank; Morgenstern, Alfred; Senekowitsch-Schmidtke, Reingard 
Title:
Fractionated intravesical radioimmunotherapy with (213)Bi-anti-EGFR-MAb is effective without toxic side-effects in a nude mouse model of advanced human bladder carcinoma. 
Abstract:
Gold standard in therapy of superficial, non-muscle invasive urothelial tumors is transurethral resection followed by intravesical instillation therapies. However, relapse is commonly observed and therefore new therapeutic approaches are needed. Application of (213)Bi-immunoconjugates targeting EGFR had shown promising results in early tumor stages. The aim of this study was the evaluation of fractionated application of (213)Bi-anti-EGFR-MAb in advanced tumor stages in a nude mouse model. Lucife...    »
 
Journal title abbreviation:
Cancer Biol Ther 
Year:
2015 
Journal volume:
16 
Journal issue:
10 
Pages contribution:
1526-34 
Language:
eng 
Print-ISSN:
1538-4047 
TUM Institution:
Frauenklinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik; Urologische Klinik und Poliklinik; Institut für Allgemeine Pathologie und pathologische Anatomie