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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Jiang, Yuanyuan; Sigmund, Felix; Reber, Josefine; Deán-Ben, Xosé Luís; Glasl, Sarah; Kneipp, Moritz; Estrada, Héctor; Razansky, Daniel; Ntziachristos, Vasilis; Westmeyer, Gil G 
Title:
Violacein as a genetically-controlled, enzymatically amplified and photobleaching-resistant chromophore for optoacoustic bacterial imaging. 
Abstract:
There is growing interest in genetically expressed reporters for in vivo studies of bacterial colonization in the context of infectious disease research, studies of the bacterial microbiome or cancer imaging and treatment. To empower non-invasive high-resolution bacterial tracking with deep tissue penetration, we herein use the genetically controlled biosynthesis of the deep-purple pigment Violacein as a photobleaching-resistant chromophore label for in vivo optoacoustic (photoacoustic) imaging...    »
 
Journal title abbreviation:
Sci Rep 
Year:
2015 
Journal volume:
Pages contribution:
11048 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
2045-2322 
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)