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Document type:
journal article 
Author(s):
Deán-Ben, X Luís; Stiel, Andre C; Jiang, Yuanyuan; Ntziachristos, Vasilis; Westmeyer, Gil G; Razansky, Daniel 
Title:
Light fluence normalization in turbid tissues via temporally unmixed multispectral optoacoustic tomography. 
Abstract:
Discerning the accurate distribution of chromophores and biomarkers by means of optoacoustic imaging is commonly challenged by the highly heterogeneous excitation light patterns resulting from strong spatial variations of tissue scattering and absorption. Here we used the light-fluence dependent switching kinetics of reversibly switchable fluorescent proteins (RSFPs), in combination with real-time acquisition of volumetric multi-spectral optoacoustic data to correct for the light fluence distrib...    »
 
Journal title abbreviation:
Opt Lett 
Year:
2015 
Journal volume:
40 
Journal issue:
20 
Pages contribution:
4691-4 
Language:
eng 
Print-ISSN:
0146-9592 
TUM Institution:
Lehrstuhl für Biologische Bildgebung; Nuklearmedizinische Klinik und Poliklinik