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Dokumenttyp:
journal article 
Autor(en):
Mykhaylyk, Olga; Sanchez-Antequera, Yolanda; Vlaskou, Dialechti; Cerda, Maria Belen; Bokharaei, Mehrdad; Hammerschmid, Edelburga; Anton, Martina; Plank, Christian 
Titel:
Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro. 
Abstract:
This chapter describes how to design and conduct experiments to deliver siRNA to adherent cell cultures in vitro by magnetic force-assisted transfection using self-assembled complexes of small interfering RNA (siRNA) and cationic lipids or polymers that are associated with magnetic nanoparticles (MNPs). These magnetic complexes are targeted to the cell surface by the application of a gradient magnetic field. A further development of the magnetic drug-targeting concept is combining it with an ult...    »
 
Zeitschriftentitel:
Methods Mol Biol 
Jahr:
2015 
Band / Volume:
1218 
Seitenangaben Beitrag:
53-106 
Sprache:
eng 
Print-ISSN:
1064-3745 
TUM Einrichtung:
Institut für experimentelle Onkologie und Therapieforschung