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Document type:
journal article 
Author(s):
Deuschle, Eva; Keller, Birgit; Siegfried, Alexandra; Manncke, Birgit; Spaeth, Tanja; Köberle, Martin; Drechsler-Hake, Doreen; Reber, Julia; Böttcher, Ralph T; Autenrieth, Stella E; Autenrieth, Ingo B; Bohn, Erwin; Schütz, Monika 
Title:
Role of ?1 integrins and bacterial adhesins for Yop injection into leukocytes in Yersinia enterocolitica systemic mouse infection. 
Abstract:
Injection of Yersinia outer proteins (Yops) into host cells by a type III secretion system is an important immune evasion mechanism of Yersinia enterocolitica (Ye). In this process Ye invasin (Inv) binds directly while Yersinia adhesin A (YadA) binds indirectly via extracellular matrix (ECM) proteins to ?1 integrins on host cells. Although leukocytes turned out to be an important target of Yop injection by Ye, it was unclear which Ye adhesins and which leukocyte receptors are required for Yop in...    »
 
Journal title abbreviation:
Int J Med Microbiol 
Year:
2016 
Journal volume:
306 
Journal issue:
Pages contribution:
77-88 
Language:
eng 
Print-ISSN:
1438-4221 
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie