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Dokumenttyp:
journal article 
Autor(en):
Kolios, A G A; Maul, J-T; Meier, B; Kerl, K; Traidl-Hoffmann, C; Hertl, M; Zillikens, D; Röcken, M; Ring, J; Facchiano, A; Mondino, C; Yawalkar, N; Contassot, E; Navarini, A A; French, L E 
Titel:
Canakinumab in adults with steroid-refractory pyoderma gangrenosum. 
Abstract:
Pyoderma gangrenosum (PG) is a rare, neutrophilic, ulcerative skin disease that is difficult to treat, especially when unresponsive to steroids.To determine whether canakinumab is an effective and safe treatment in PG.Five adult patients with clinically and histologically confirmed steroid-refractory PG were enrolled in this prospective open-label study. They received canakinumab 150 mg subcutaneously at week 0 with an optional 150 mg at week 2 in case of an inadequate response [Physician's Glob...    »
 
Zeitschriftentitel:
Br J Dermatol 
Jahr:
2015 
Band / Volume:
173 
Heft / Issue:
Seitenangaben Beitrag:
1216-23 
Sprache:
eng 
Print-ISSN:
0007-0963 
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie