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Dokumenttyp:
journal article 
Autor(en):
Avitabile, Simona; Odorisio, Teresa; Madonna, Stefania; Eyerich, Stefanie; Guerra, Liliana; Eyerich, Kilian; Zambruno, Giovanna; Cavani, Andrea; Cianfarani, Francesca 
Titel:
Interleukin-22 Promotes Wound Repair in Diabetes by Improving Keratinocyte Pro-Healing Functions. 
Abstract:
Impaired re-epithelialization, imbalanced expression of cytokines and growth factors, and vascular disease contribute to healing impairment in diabetes. IL-22, a pro-inflammatory cytokine mediating a cross-talk between immune system and epithelial cells, has been shown to have a role in repair processes. In this study we aimed to investigate IL-22 regenerative potential in the poor healing context of diabetic wounds. By using streptozotocin-induced diabetic mice, we demonstrated that IL-22 wound...    »
 
Zeitschriftentitel:
J Invest Dermatol 
Jahr:
2015 
Band / Volume:
135 
Heft / Issue:
11 
Seitenangaben Beitrag:
2862-70 
Sprache:
eng 
Print-ISSN:
0022-202X 
TUM Einrichtung:
Institut für Molekulare Allergologie und Umweltforschung; Klinik und Poliklinik für Dermatologie und Allergologie