User: Guest  Login
Document type:
journal article 
Author(s):
Meindl, A; Ramser, J; Hauke, J; Hahnen, E 
Title:
Genetic aspects of hereditary breast and ovarian cancer: options and limits 
Abstract:
Recent studies have documented the genetic heterogeneity of familial breast and ovarian cancer. In addition to BRCA1 and BRCA2, more than 20 risk genes for hereditary breast and ovarian cancer, explaining about one third of familial cases, have been identified so far. Additionally, polygenic factors have been discovered that may explain about 16 % of the genetic burden of BRCA1/2-negative cases. Today, routine diagnostics using gene panels in addition to BRCA1/2 testing is already offered in man...    »
 
Journal title abbreviation:
Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V. 
Year:
2015 
Journal volume:
27 
Journal issue:
Pages contribution:
202-+ 
Language:
de 
Print-ISSN:
0936-5931 
TUM Institution:
Frauenklinik und Poliklinik