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Dokumenttyp:
journal article 
Autor(en):
Mueller, Tara C; Bachmann, Jeannine; Prokopchuk, Olga; Friess, Helmut; Martignoni, Marc E 
Titel:
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia--can findings from animal models be translated to humans? 
Abstract:
Cachexia is a multi-factorial, systemic syndrome that especially affects patients with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival and quality of life. The most important clinical feature of cachexia is the excessive wasting of skeletal muscle mass. Currently, an effective treatment is still lacking and the search for therapeutic targets continues. Even though a substantial number of animal studies have contributed to a better understanding of the unde...    »
 
Zeitschriftentitel:
BMC Cancer 
Jahr:
2016 
Band / Volume:
16 
Seitenangaben Beitrag:
75 
Sprache:
eng 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik