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Document type:
journal article 
Author(s):
Greißel, A; Culmes, M; Napieralski, R; Wagner, E; Gebhard, H; Schmitt, M; Zimmermann, A; Eckstein, H-H; Zernecke, A; Pelisek, J 
Title:
Alternation of histone and DNA methylation in human atherosclerotic carotid plaques. 
Abstract:
Little is known about epigenetics and its possible role in atherosclerosis. We here analysed histone and DNA methylation and the expression of corresponding methyltransferases in early and advanced human atherosclerotic carotid lesions in comparison to healthy carotid arteries. Western Blotting was performed on carotid plaques from our biobank with early (n=60) or advanced (n=60) stages of atherosclerosis and healthy carotid arteries (n=12) to analyse di-methylation patterns of histone H3 at pos...    »
 
Journal title abbreviation:
Thromb Haemost 
Year:
2015 
Journal volume:
114 
Journal issue:
Pages contribution:
390-402 
Language:
eng 
Print-ISSN:
0340-6245 
TUM Institution:
Klinik für Gefäßchirurgie