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Dokumenttyp:
journal article 
Autor(en):
Bauer, Lukas; Takacs, Agnes; Slotta-Huspenina, Julia; Langer, Rupert; Becker, Karen; Novotny, Alexander; Ott, Katja; Walch, Axel; Hapfelmeier, Alexander; Keller, Gisela 
Titel:
Clinical Significance of NOTCH1 and NOTCH2 Expression in Gastric Carcinomas: An Immunohistochemical Study. 
Abstract:
NOTCH signaling can exert oncogenic or tumor suppressive functions and can contribute to chemotherapy resistance in cancer. In this study, we aimed to clarify the clinicopathological significance and the prognostic and predictive value of NOTCH1 and NOTCH2 expression in gastric cancer (GC).NOTCH1 and NOTCH2 expression was determined immunohistochemically in 142 primarily resected GCs using tissue microarrays and in 84 pretherapeutic biopsies from patients treated by neoadjuvant chemotherapy. The...    »
 
Zeitschriftentitel:
Front Oncol 
Jahr:
2015 
Band / Volume:
Seitenangaben Beitrag:
94 
Sprache:
eng 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie; Chirurgiesche Klinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie