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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Spenlé, Caroline; Gasser, Isabelle; Saupe, Falk; Janssen, Klaus-Peter; Arnold, Christiane; Klein, Annick; van der Heyden, Michael; Mutterer, Jérome; Neuville-Méchine, Agnès; Chenard, Marie-Pierre; Guenot, Dominique; Esposito, Irene; Slotta-Huspenina, Julia; Ambartsumian, Noona; Simon-Assmann, Patricia; Orend, Gertraud 
Title:
Spatial organization of the tenascin-C microenvironment in experimental and human cancer. 
Abstract:
The extracellular matrix (ECM) molecule tenascin-C (TNC) promotes tumor progression. This has recently been demonstrated in the stochastic murine RIP1-Tag2 insulinoma model, engineered to either express TNC abundantly or to be devoid of TNC. However, our knowledge about organization of the TNC microenvironment is scant. Here we determined the spatial distribution of TNC together with other ECM molecules in murine RIP1-Tag2 insulinoma and human cancer tissue (insulinoma and colorectal carcinoma)....    »
 
Journal title abbreviation:
Cell Adh Migr 
Year:
2015 
Journal volume:
Journal issue:
1-2 
Pages contribution:
4-13 
Language:
eng 
Print-ISSN:
1933-6918 
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie