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Document type:
journal article 
Author(s):
Grze?kowiak, Bartosz F; Sánchez-Antequera, Yolanda; Hammerschmid, Edelburga; Döblinger, Markus; Eberbeck, Dietmar; Wo?niak, Anna; S?omski, Ryszard; Plank, Christian; Mykhaylyk, Olga 
Title:
Nanomagnetic activation as a way to control the efficacy of nucleic acid delivery. 
Abstract:
To explore the potential of magnetofection in delivering pDNA to primary mouse embryonic fibroblasts (PMEFs) and porcine fetal fibroblasts (PFFs) and investigate an effect of magnetic cell labeling on transfection efficacy.The formulation and a dose of the magnetic vector were optimized. The efficacy of the procedure was quantified by vector internalization, transgene expression and cell iron loading upon specific labeling with Ab-conjugated magnetic beads or non-specific labeling with MNPs.Up t...    »
 
Journal title abbreviation:
Pharm Res 
Year:
2015 
Journal volume:
32 
Journal issue:
Pages contribution:
103-21 
Language:
eng 
Print-ISSN:
0724-8741 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung