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Document type:
journal article 
Author(s):
Weidle, Ulrich H; Birzele, Fabian; Krüger, Achim 
Title:
Molecular targets and pathways involved in liver metastasis of colorectal cancer. 
Abstract:
We here summarize the current view of molecular mechanisms involved in the dissemination process of colorectal cancer cells to the liver as deduced from preclinical models. We focus on molecular aspects of the current understanding of the biology of liver metastases formation and survival, both being crucial for identification and validation of possible therapeutic targets and review the latest findings elucidating some features of the liver as a metastatic niche. In more detail, we outline the...    »
 
Journal title abbreviation:
Clin Exp Metastasis 
Year:
2015 
Journal volume:
32 
Journal issue:
Pages contribution:
623-35 
Language:
eng 
Print-ISSN:
0262-0898 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung