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Dokumenttyp:
Zeitschriftenaufsatz 
Autor(en):
Cattani-Scholz, A.; Pedone, D.; Dubey, M.; Neppl, S.; Nickel, B.; Feulner, P.; Schwartz, J.; Abstreiter, G.; Tornow, M. 
Titel:
Organophosphonate based PNA-functionalization of silicon nanowires for label-free DNA detection 
Abstract:
We investigated hydroxyalkylphosphonate monolayers as a novel platform for the biofunctionalization of silicon-based field effect sensor devices. This included a detailed study of the thin film properties of organophosphonate films on Si substrates using several surface analysis techniques, including AFM, ellipsometry, contact angle, X-ray photoelectron spectroscopy (XPS), X-ray reflectivity, and current-voltage characteristics in electrolyte solution. Our results indicate the formation of a den...    »
 
Stichworte:
biosensor · DNA/PNA hybridization · surface characterization · XPS · X-ray reflectivity · organophosphonate monolayers · heterobifunctional linker · silicon nanowire device 
Zeitschriftentitel:
ACS Nano Org, VOL. 2 ▪ NO. 8 ▪ 1653–1660 ▪ 2008 
Jahr:
2008 
Jahr / Monat:
2008-07 
Quartal:
3. Quartal 
Monat:
Jul 
Seitenangaben Beitrag:
1653-1660