User: Guest  Login
Document type:
journal article 
Author(s):
de Jong, Johann; Akhtar, Waseem; Badhai, Jitendra; Rust, Alistair G; Rad, Roland; Hilkens, John; Berns, Anton; van Lohuizen, Maarten; Wessels, Lodewyk F A; de Ridder, Jeroen 
Title:
Chromatin landscapes of retroviral and transposon integration profiles. 
Abstract:
The ability of retroviruses and transposons to insert their genetic material into host DNA makes them widely used tools in molecular biology, cancer research and gene therapy. However, these systems have biases that may strongly affect research outcomes. To address this issue, we generated very large datasets consisting of ~ 120,000 to ~ 180,000 unselected integrations in the mouse genome for the Sleeping Beauty (SB) and piggyBac (PB) transposons, and the Mouse Mammary Tumor Virus (MMTV). We ana...    »
 
Journal title abbreviation:
PLoS Genet 
Year:
2014 
Journal volume:
10 
Journal issue:
Pages contribution:
e1004250 
Language:
eng 
Print-ISSN:
1553-7390 
TUM Institution:
II. Medizinische Klinik und Poliklinik