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Document type:
journal article 
Author(s):
Weinspach, Dirk; Seubert, Bastian; Schaten, Susanne; Honert, Katja; Sebens, Susanne; Altevogt, Peter; Krüger, Achim 
Title:
Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth. 
Abstract:
Expression of the L1 cell adhesion molecule (L1CAM) is frequently increased in cancer patients compared to healthy individuals and also linked with bad prognosis of solid tumours. Previously, we could show that full-length L1CAM promotes metastasis formation via up-regulation of gelatinolytic activity in fibrosarcoma. In this study, we aimed to extend this finding to haematogenous malignancies and carcinomas, and to specifically elucidate the impact of L1CAM on major steps of the metastatic casc...    »
 
Journal title abbreviation:
Clin Exp Metastasis 
Year:
2014 
Journal volume:
31 
Journal issue:
Pages contribution:
87-100 
Language:
eng 
Print-ISSN:
0262-0898 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung