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Document type:
journal article 
Author(s):
Engels, Melanie; Bilgic, Esra; Pinto, Antonio; Vasquez, Edwin; Wollschläger, Lena; Steinbrenner, Holger; Kellermann, Kristine; Akhyari, Payam; Lichtenberg, Artur; Boeken, Udo 
Title:
A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage. 
Abstract:
Cardiopulmonary bypass (CPB) is a commonly used technique in cardiac surgery. CPB is however associated with a strong induction of systemic inflammatory response syndrome (SIRS) which in conjunction with ischemia and reperfusion may lead to multiple organ failure. The aim of the study was to establish and characterize a CPB rat model incorporating deep hypothermic circulatory arrest with a specific focus on the extent of the inflammatory reactions and organ damage as a groundwork for novel thera...    »
 
Journal title abbreviation:
J Inflamm (Lond) 
Year:
2014 
Journal volume:
11 
Pages contribution:
26 
Language:
eng 
TUM Institution:
Klinik für Anästhesiologie