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Document type:
journal article 
Gibbs, Peter; Gebski, Val; Van Buskirk, Mark; Thurston, Kenneth; Cade, David N; Van Hazel, Guy A; SIRFLOX Study Group; Amin, Pradip; Angelelli, Bruna; Balosso, Jacques; Beny, Alex; Bloomgarden, Daniel; Boucher, Eveline; Brown, Michael; Bruch, Harald-Robert; Bui, James; Burge, Matthew; Cardaci, Giuseppe; Carlisle, James; Chen, Yi-Jen; Chevallier, Patrick; Clarke, Stephen; Coveler, Andrew; Craninx, Michel; Delanoit, Thierry; Deleporte, Amélie; Eliadis, Paul; Facchini, Francis; Ferguson, Thomas; Fe...    »
Selective Internal Radiation Therapy (SIRT) with yttrium-90 resin microspheres plus standard systemic chemotherapy regimen of FOLFOX versus FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer: the SIRFLOX study. 
In colorectal cancer (CRC), unresectable liver metastases are linked to poor prognosis. Systemic chemotherapy with regimens such as FOLFOX (combination of infusional 5-fluorouracil, leucovorin and oxaliplatin) is the standard first-line treatment. The SIRFLOX trial was designed to assess the efficacy and safety of combining FOLFOX-based chemotherapy with Selective Internal Radiation Therapy (SIRT or radioembolisation) using yttrium-90 resin microspheres (SIR-SpheresR; Sirtex Medical Limited, No...    »
Journal title abbreviation:
BMC Cancer 
Journal volume:
Pages contribution:
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik