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Document type:
journal article 
Author(s):
Heidegger, Simon; van den Brink, Marcel R M; Haas, Tobias; Poeck, Hendrik 
Title:
The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation. 
Abstract:
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with curative potential for certain aggressive hematopoietic malignancies. Its success is limited by acute graft-versus-host disease (GVHD), a life-threatening complication that occurs when allo-reactive donor T cells attack recipient organs. There is growing evidence that microbes and innate pattern-recognition receptors (PRRs) such as toll-like receptors (TLR) and nod-like receptors (NLR) are critically involv...    »
 
Journal title abbreviation:
Front Immunol 
Year:
2014 
Journal volume:
Pages contribution:
337 
Language:
eng 
TUM Institution:
III. Medizinische Klinik und Poliklinik