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Dokumenttyp:
journal article 
Autor(en):
Bartelheim, Kerstin; Sumerauer, David; Behrends, Uta; Kodetova, Daniela; Kucera, Filip; Leuschner, Ivo; Neumayer, Petra; Oyen, Florian; Rübe, Christian; Siebert, Reiner; Schneppenheim, Reinhard; Seeringer, Angela; Vasovcak, Peter; Frühwald, Michael C 
Titel:
Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB). 
Abstract:
Rhabdoid tumors are rare but highly aggressive malignancies of infancy and early childhood with a generally unfavorable prognosis. Despite a wide variety of anatomic locations rhabdoid tumors share mutational inactivation of the SWI/SNF (SWItch/Sucrose NonFermentable) core component gene SMARCB1 (also known as INI1, hSNF5 or BAF47) in chromosome 22. As this inactivation usually results in loss of SMARCB1 expression, detectable by an antibody against the SMARCB1 protein, the accurate diagnosis of...    »
 
Zeitschriftentitel:
Cancer Genet 
Jahr:
2014 
Band / Volume:
207 
Heft / Issue:
Seitenangaben Beitrag:
379-83 
Sprache:
eng 
Print-ISSN:
2210-7762 
TUM Einrichtung:
Kinderklinik und Poliklinik