Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Fiedler, K Anette; Mehilli, Julinda; Kufner, Sebastian; Schlichting, Anna; Ibrahim, Tareq; Sibbing, Dirk; Ott, Ilka; Schunkert, Heribert; Laugwitz, Karl-Ludwig; Kastrati, Adnan; Schulz, Stefanie 
Titel:
Randomised, double-blind trial on the value of tapered discontinuation of clopidogrel maintenance therapy after drug-eluting stent implantation. Intracoronary Stenting and Antithrombotic Regimen: CAUTION in Discontinuing Clopidogrel Therapy--ISAR-CAUTION. 
Abstract:
There is little evidence on the optimal mode of clopidogrel discontinuation. Epidemiological studies observed clustering of thrombotic events after cessation of chronic clopidogrel therapy. The underlying mechanism has been ascribed to transient platelet hyper-reactivity. Gradual tapering of clopidogrel may have the potential to attenuate this phenomenon. The objective of the present study was to assess whether in patients with drug-eluting stents (DES) gradual discontinuation of clopidogrel mai...    »
 
Zeitschriftentitel:
Thromb Haemost 
Jahr:
2014 
Band / Volume:
111 
Heft / Issue:
Seitenangaben Beitrag:
1041-9 
Sprache:
eng 
Print-ISSN:
0340-6245 
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen; I. Medizinische Klinik und Poliklinik