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Dokumenttyp:
journal article 
Autor(en):
Whitney, Paul G; Bär, Eva; Osorio, Fabiola; Rogers, Neil C; Schraml, Barbara U; Deddouche, Safia; LeibundGut-Landmann, Salomé; Reis e Sousa, Caetano 
Titel:
Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection. 
Abstract:
Host protection from fungal infection is thought to ensue in part from the activity of Syk-coupled C-type lectin receptors and MyD88-coupled toll-like receptors in myeloid cells, including neutrophils, macrophages and dendritic cells (DCs). Given the multitude of cell types and receptors involved, elimination of a single pathway for fungal recognition in a cell type such as DCs, primarily known for their ability to prime T cell responses, would be expected to have little effect on innate resista...    »
 
Zeitschriftentitel:
PLoS Pathog 
Jahr:
2014 
Band / Volume:
10 
Heft / Issue:
Seitenangaben Beitrag:
e1004276 
Sprache:
eng 
Print-ISSN:
1553-7366 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene