Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Schwartz, Christian; Oeser, Katharina; Prazeres da Costa, Clarissa; Layland, Laura E; Voehringer, David 
Titel:
T cell-derived IL-4/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils. 
Abstract:
Schistosomiasis is a severe and chronic disease caused by the parasitic trematode Schistosoma mansoni after deposition of eggs in the liver and intestines. The immune response to S. mansoni eggs is characterized by increased Th2 cells, eosinophilia, and high serum IgE levels. Granulomas are formed around the eggs to protect the organs against tissue damage caused by toxic products that are secreted from the eggs. Egg-derived components have further been shown to activate the IgE-mediated release...    »
 
Zeitschriftentitel:
J Immunol 
Jahr:
2014 
Band / Volume:
193 
Heft / Issue:
Seitenangaben Beitrag:
3590-9 
Sprache:
eng 
Print-ISSN:
0022-1767 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene