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Dokumenttyp:
journal article 
Autor(en):
Engler, Daniela B; Reuter, Sebastian; van Wijck, Yolanda; Urban, Sabine; Kyburz, Andreas; Maxeiner, Joachim; Martin, Helen; Yogev, Nir; Waisman, Ari; Gerhard, Markus; Cover, Timothy L; Taube, Christian; Müller, Anne 
Titel:
Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10. 
Abstract:
The prevalence of allergic asthma and other atopic diseases has reached epidemic proportions in large parts of the developed world. The gradual loss of the human indigenous microbiota has been held responsible for this trend. The bacterial pathogen Helicobacter pylori is a constituent of the normal gastric microbiota whose presence has been inversely linked to allergy and asthma in humans and experimental models. Here we show that oral or i.p. tolerization with H. pylori extract prevents the air...    »
 
Zeitschriftentitel:
Proc Natl Acad Sci U S A 
Jahr:
2014 
Band / Volume:
111 
Heft / Issue:
32 
Seitenangaben Beitrag:
11810-5 
Sprache:
eng 
Print-ISSN:
0027-8424 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene