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Document type:
journal article 
Author(s):
Engler, Daniela B; Reuter, Sebastian; van Wijck, Yolanda; Urban, Sabine; Kyburz, Andreas; Maxeiner, Joachim; Martin, Helen; Yogev, Nir; Waisman, Ari; Gerhard, Markus; Cover, Timothy L; Taube, Christian; Müller, Anne 
Title:
Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10. 
Abstract:
The prevalence of allergic asthma and other atopic diseases has reached epidemic proportions in large parts of the developed world. The gradual loss of the human indigenous microbiota has been held responsible for this trend. The bacterial pathogen Helicobacter pylori is a constituent of the normal gastric microbiota whose presence has been inversely linked to allergy and asthma in humans and experimental models. Here we show that oral or i.p. tolerization with H. pylori extract prevents the air...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2014 
Journal volume:
111 
Journal issue:
32 
Pages contribution:
11810-5 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene