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Document type:
journal article 
Author(s):
Beil, Jane; Buch, Thorsten 
Title:
Generation of bacterial artificial chromosome (BAC) transgenic mice. 
Abstract:
Transgenic mice are among the most helpful tools to study the role of genes in physiological conditions. In this protocol, we describe the generation of bacterial artificial chromosome (BACs) constructs, which are used to express a gene of interest under a particular promoter. BACs as driver of transgenes have the advantage that a characterization of transcriptional control elements is unnecessary and the construct's size usually reduces position effects from random integration. In the following...    »
 
Journal title abbreviation:
Methods Mol Biol 
Year:
2014 
Journal volume:
1194 
Pages contribution:
157-69 
Language:
eng 
Print-ISSN:
1064-3745 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene