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Dokumenttyp:
journal article 
Autor(en):
Beil, Jane; Buch, Thorsten 
Titel:
Generation of bacterial artificial chromosome (BAC) transgenic mice. 
Abstract:
Transgenic mice are among the most helpful tools to study the role of genes in physiological conditions. In this protocol, we describe the generation of bacterial artificial chromosome (BACs) constructs, which are used to express a gene of interest under a particular promoter. BACs as driver of transgenes have the advantage that a characterization of transcriptional control elements is unnecessary and the construct's size usually reduces position effects from random integration. In the following...    »
 
Zeitschriftentitel:
Methods Mol Biol 
Jahr:
2014 
Band / Volume:
1194 
Seitenangaben Beitrag:
157-69 
Sprache:
eng 
Print-ISSN:
1064-3745 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene