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Document type:
journal article 
Author(s):
Simpson, Claire L; Wojciechowski, Robert; Oexle, Konrad; Murgia, Federico; Portas, Laura; Li, Xiaohui; Verhoeven, Virginie J M; Vitart, Veronique; Schache, Maria; Hosseini, S Mohsen; Hysi, Pirro G; Raffel, Leslie J; Cotch, Mary Frances; Chew, Emily; Klein, Barbara E K; Klein, Ronald; Wong, Tien Yin; van Duijn, Cornelia M; Mitchell, Paul; Saw, Seang Mei; Fossarello, Maurizio; Wang, Jie Jin; DCCT/EDIC Research Group; Pola?ek, Ozren; Campbell, Harry; Rudan, Igor; Oostra, Ben A; Uitterlinden, André...    »
 
Title:
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. 
Abstract:
Refractive error (RE) is a complex, multifactorial disorder characterized by a mismatch between the optical power of the eye and its axial length that causes object images to be focused off the retina. The two major subtypes of RE are myopia (nearsightedness) and hyperopia (farsightedness), which represent opposite ends of the distribution of the quantitative measure of spherical refraction. We performed a fixed effects meta-analysis of genome-wide association results of myopia and hyperopia fro...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
e107110 
Language:
eng 
TUM Institution:
Institut für Humangenetik