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Dokumenttyp:
journal article 
Autor(en):
Prager, Matthias; Durmus, Tahir; Büttner, Janine; Molnar, Tamas; de Jong, Dirk J; Drenth, Joost Ph; Baumgart, Daniel C; Sturm, Andreas; Farkas, Klaudia; Witt, Heiko; Büning, Carsten 
Titel:
Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn's disease. 
Abstract:
Myosin IXb (MYO9B) is involved in the regulation of epithelial barrier function. We hypothesized that MYO9B variants are associated with increased intestinal permeability measured in patients with Crohn's disease (CD), where barrier dysfunction is crucially involved in disease development.We sequenced MYO9B and genotyped five MYO9B variants (rs1545620, rs1457092, rs2279003, rs2305764 and rs2279002) and correlated these data to measurement of intestinal permeability in German CD patients (n = 122...    »
 
Zeitschriftentitel:
Scand J Gastroenterol 
Jahr:
2014 
Band / Volume:
49 
Heft / Issue:
10 
Seitenangaben Beitrag:
1191-200 
Sprache:
eng 
Print-ISSN:
0036-5521 
TUM Einrichtung:
Klinik für Ernährungsmedizin