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Dokumenttyp:
journal article 
Autor(en):
Lies, Barbara; Gil, Víctor; Groneberg, Dieter; Seidler, Barbara; Saur, Dieter; Wischmeyer, Erhard; Jiménez, Marcel; Friebe, Andreas 
Titel:
Interstitial cells of Cajal mediate nitrergic inhibitory neurotransmission in the murine gastrointestinal tract. 
Abstract:
Nitric oxide (NO) is a major inhibitory neurotransmitter in the gastrointestinal (GI) tract. Its main effector, NO-sensitive guanylyl cyclase (NO-GC), is expressed in several GI cell types, including smooth muscle cells (SMC), interstitial cells of Cajal (ICC), and fibroblast-like cells. Up to date, the interplay between neurons and these cells to initiate a nitrergic inhibitory junction potential (IJP) is unclear. Here, we investigate the origin of the nitrergic IJP in murine fundus and colon....    »
 
Zeitschriftentitel:
Am J Physiol Gastrointest Liver Physiol 
Jahr:
2014 
Band / Volume:
307 
Heft / Issue:
Seitenangaben Beitrag:
G98-106 
Sprache:
eng 
Print-ISSN:
0193-1857 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik