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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Jia, Hongbo; Varga, Zsuzsanna; Sakmann, Bert; Konnerth, Arthur 
Title:
Linear integration of spine Ca2+ signals in layer 4 cortical neurons in vivo. 
Abstract:
Sensory information reaches the cortex through synchronously active thalamic axons, which provide a strong drive to layer 4 (L4) cortical neurons. Because of technical limitations, the dendritic signaling processes underlying the rapid and efficient activation of L4 neurons in vivo remained unknown. Here we introduce an approach that allows the direct monitoring of single dendritic spine Ca(2+) signals in L4 spiny stellate cells of the vibrissal mouse cortex in vivo. Our results demonstrate that...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2014 
Journal volume:
111 
Journal issue:
25 
Pages contribution:
9277-82 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Neurowissenschaften