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Document type:
journal article 
Author(s):
Mease, Rebecca A; Krieger, Patrik; Groh, Alexander 
Title:
Cortical control of adaptation and sensory relay mode in the thalamus. 
Abstract:
A major synaptic input to the thalamus originates from neurons in cortical layer 6 (L6); however, the function of this cortico-thalamic pathway during sensory processing is not well understood. In the mouse whisker system, we found that optogenetic stimulation of L6 in vivo results in a mixture of hyperpolarization and depolarization in the thalamic target neurons. The hyperpolarization was transient, and for longer L6 activation (>200 ms), thalamic neurons reached a depolarized resting membran...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2014 
Journal volume:
111 
Journal issue:
18 
Pages contribution:
6798-803 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Neurowissenschaften