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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Cun, Yanping; Tang, Lin; Yan, Jie; He, Chao; Li, Yang; Hu, Zhian; Xia, Jianxia 
Title:
Orexin A attenuates the sleep-promoting effect of adenosine in the lateral hypothalamus of rats. 
Abstract:
Orexin neurons within the lateral hypothalamus play a crucial role in the promotion and maintenance of arousal. Studies have strongly suggested that orexin neurons are an important target in endogenous adenosine-regulated sleep homeostasis. Orexin A induces a robust increase in the firing activity of orexin neurons, while adenosine has an inhibitory effect. Whether the excitatory action of orexins in the lateral hypothalamus actually promotes wakefulness and reverses the sleep-producing effect o...    »
 
Journal title abbreviation:
Neurosci Bull 
Year:
2014 
Journal volume:
30 
Journal issue:
Pages contribution:
877-86 
Language:
eng 
Print-ISSN:
1673-7067 
TUM Institution:
Institut für Neurowissenschaften