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Document type:
journal article 
Author(s):
Castro-Rojas, Cyd; Deason, Krystin; Hussain, Rehana Z; Hayardeny, Liat; Cravens, Petra C; Yarovinsky, Felix; Eagar, Todd N; Arellano, Benjamine; Stüve, Olaf 
Title:
Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance. 
Abstract:
Immune surveillance of the CNS is critical for preventing infections; however, there is no accepted experimental model to assess the risk of infection when utilizing disease-modifying agents. We tested two approved agents for patients with multiple sclerosis (MS), glatiramer acetate and fingolimod, in an experimental model of CNS immune surveillance. C57BL/6 mice were infected with the ME49 strain of the neuroinvasive parasite Toxoplasma gondii (T. gondii) and then treated with GA and fingolimo...    »
 
Journal title abbreviation:
J Neuroimmunol 
Year:
2014 
Journal volume:
276 
Journal issue:
1-2 
Pages contribution:
232-5 
Language:
eng 
Print-ISSN:
0165-5728 
TUM Institution:
Neurologische Klinik und Poliklinik