Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Castro-Rojas, Cyd; Deason, Krystin; Hussain, Rehana Z; Hayardeny, Liat; Cravens, Petra C; Yarovinsky, Felix; Eagar, Todd N; Arellano, Benjamine; Stüve, Olaf 
Titel:
Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance. 
Abstract:
Immune surveillance of the CNS is critical for preventing infections; however, there is no accepted experimental model to assess the risk of infection when utilizing disease-modifying agents. We tested two approved agents for patients with multiple sclerosis (MS), glatiramer acetate and fingolimod, in an experimental model of CNS immune surveillance. C57BL/6 mice were infected with the ME49 strain of the neuroinvasive parasite Toxoplasma gondii (T. gondii) and then treated with GA and fingolimo...    »
 
Zeitschriftentitel:
J Neuroimmunol 
Jahr:
2014 
Band / Volume:
276 
Heft / Issue:
1-2 
Seitenangaben Beitrag:
232-5 
Sprache:
eng 
Print-ISSN:
0165-5728 
TUM Einrichtung:
Neurologische Klinik und Poliklinik