User: Guest  Login
Document type:
journal article 
Author(s):
Menge, Til; Stüve, Olaf; Kieseier, Bernd C; Hartung, Hans-Peter 
Title:
Alemtuzumab: the advantages and challenges of a novel therapy in MS. 
Abstract:
Our understanding of the pathogenesis of multiple sclerosis has increased considerably, leading to the development of novel therapeutic approaches and compounds. Several agents have undergone clinical testing and have recently received market authorization or are being evaluated for approval. Alemtuzumab is a humanized monoclonal antibody that rapidly depletes CD52+ cells of the lymphoid lineage from peripheral blood, but spares lymphoid precursor cells. Clinical efficacy and safety data from cl...    »
 
Journal title abbreviation:
Neurology 
Year:
2014 
Journal volume:
83 
Journal issue:
Pages contribution:
87-97 
Language:
eng 
Print-ISSN:
0028-3878 
TUM Institution:
Neurologische Klinik und Poliklinik