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Dokumenttyp:
journal article 
Autor(en):
Depboylu, Candan; Klietz, Martin; Maurer, Lukas; Oertel, Wolfgang H; Kobayashi, Kazuto; Weihe, Eberhard; Höglinger, Günter U; Schäfer, Martin K-H 
Titel:
Transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation. 
Abstract:
Mice that express green fluorescent protein (GFP) under the control of tyrosine hydroxylase (TH) gene promoter were used to visualize transcriptional as well as structural regulation of TH cells following prolonged dopaminergic denervation. A unilateral lesion of the medial forebrain bundle was induced by 6-hydroxydopamine. In the unlesioned contralateral striatum and nucleus accumbens surprisingly high numbers of resident GFP-positive neurons (about 2653 and 422 per striatum and accumbens, resp...    »
 
Zeitschriftentitel:
J Chem Neuroanat 
Jahr:
2014 
Band / Volume:
61-62 
Seitenangaben Beitrag:
169-75 
Sprache:
eng 
Print-ISSN:
0891-0618 
TUM Einrichtung:
Neurologische Klinik und Poliklinik