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Dokumenttyp:
journal article 
Autor(en):
Shirai, Ayumi; Yamazaki, Osamu; Horita, Shoko; Nakamura, Motonobu; Satoh, Nobuhiko; Yamada, Hideomi; Suzuki, Masashi; Kudo, Akihiko; Kawakami, Hayato; Hofmann, Franz; Nishiyama, Akira; Kume, Haruki; Enomoto, Yutaka; Homma, Yukio; Seki, George 
Titel:
Angiotensin II dose-dependently stimulates human renal proximal tubule transport by the nitric oxide/guanosine 3',5'-cyclic monophosphate pathway. 
Abstract:
Stimulation of renal proximal tubule (PT) transport by angiotensin II (Ang II) is critical for regulation of BP. Notably, in rats, mice, and rabbits, the regulation of PT sodium transport by Ang II is biphasic: transport is stimulated by picomolar to nanomolar concentrations of Ang II but inhibited by nanomolar to micromolar concentrations of Ang II. However, little is known about the effects of Ang II on human PT transport. By functional analysis with isolated PTs obtained from nephrectomy surg...    »
 
Zeitschriftentitel:
J Am Soc Nephrol 
Jahr:
2014 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
1523-32 
Sprache:
eng 
Print-ISSN:
1046-6673 
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie