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Document type:
journal article 
Author(s):
Skabytska, Yuliya; Wölbing, Florian; Günther, Claudia; Köberle, Martin; Kaesler, Susanne; Chen, Ko-Ming; Guenova, Emmanuella; Demircioglu, Doruk; Kempf, Wolfgang E; Volz, Thomas; Rammensee, Hans-Georg; Schaller, Martin; Röcken, Martin; Götz, Friedrich; Biedermann, Tilo 
Title:
Cutaneous innate immune sensing of Toll-like receptor 2-6 ligands suppresses T cell immunity by inducing myeloid-derived suppressor cells. 
Abstract:
Skin is constantly exposed to bacteria and antigens, and cutaneous innate immune sensing orchestrates adaptive immune responses. In its absence, skin pathogens can expand, entering deeper tissues and leading to life-threatening infectious diseases. To characterize skin-driven immunity better, we applied living bacteria, defined lipopeptides, and antigens cutaneously. We found suppression of immune responses due to cutaneous infection with Gram-positive S. aureus, which was based on bacterial lip...    »
 
Journal title abbreviation:
Immunity 
Year:
2014 
Journal volume:
41 
Journal issue:
Pages contribution:
762-75 
Language:
eng 
Print-ISSN:
1074-7613 
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie