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Dokumenttyp:
journal article 
Autor(en):
Kaesler, Susanne; Volz, Thomas; Skabytska, Yuliya; Köberle, Martin; Hein, Ulrike; Chen, Ko-Ming; Guenova, Emmanuella; Wölbing, Florian; Röcken, Martin; Biedermann, Tilo 
Titel:
Toll-like receptor 2 ligands promote chronic atopic dermatitis through IL-4-mediated suppression of IL-10. 
Abstract:
Atopic dermatitis (AD) is a T cell-mediated inflammatory skin disease, with TH2 cells initiating acute flares. This inflamed skin is immediately colonized with Staphylococcus aureus, which provides potent Toll-like receptor (TLR) 2 ligands. However, the effect of TLR2 ligands on the development of TH2-mediated AD inflammation remains unclear.We investigated the progression of TH2 cell-mediated dermatitis after TLR2 activation.Using models for acute AD with TH2 cells initiating cutaneous inflamma...    »
 
Zeitschriftentitel:
J Allergy Clin Immunol 
Jahr:
2014 
Band / Volume:
134 
Heft / Issue:
Seitenangaben Beitrag:
92-9 
Sprache:
eng 
Print-ISSN:
0091-6749 
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie